Voir Marvel Comics X-Men (1992) Seasons 1 – 5 - Episode 20

"Time Fugitives" begins in New York City, in 3999 AD. Here Time is changing itself. Cable uses his time device and sees that Bishop traveled from 2055 AD to the present to stop a plague, which Apocalypse started. Because he stopped the virus from being created, the antibodies that protected mutants from further plagues were never created.